Volos Summer School of Human Genetics 2023
Organised yearly in summer at the University of Thessaly
Join us for 4 days of lectures and workshops revolving around genome-wide association studies.
Location
Join us in sunny Volos (Βόλος) on the coast of Thessaly. You will find a range of accommodation facilities around the summer school venue.
The Venue
Vocational Training Center – University of Thessaly
Giannitson & Lahana, Palaia,
Complex Tsalapatas,
Zip: 38334, Volos,
Tel: +30 24210 06366-68
Fax: +30 24210 06487
e-mail: kdvm@uth.gr
How to get there
Follow this link to Google Maps.
Course overview
The Volos Summer School will cover a range of topics surrounding the human genetics of complex traits, with a focus on the computational and statistical analysis of genome-wide data. Areas of focus will be the conduct of genome-wide association studies, meta-analysis of several studies, and the joint analysis of multiple diseases/traits to understand pleiotropy.
The course will be split into seminars and workshops. The former will provide background theory to the topics covered, while the latter will allow students to implement some of the analysis concepts presented during the seminars.
Students will obtain the skills to manipulate and analyse large data sets in a Unix environment and a basic understanding of scripting and programming skills.
Students will also have the opportunity to discuss their own projects and ideas with experienced researchers in the field. At the start of the summer school, students will be asked to form teams and design a genetic study, which will be discussed at the end of the program and evaluated by the instructors. The best project idea will receive an award.
The main objectives of this summer school are to provide students with a solid grounding in the use of bioinformatics tools, key software, statistical and visualization methods and their various applications in genome studies.
Due to the range of material covered, this is an intense three-day course and will require the active participation of students.
Who can attend ?
The Volos Summer School is intended for early career researchers (graduate students or post-docs) interested to learn about the genetics of complex human traits and gain practical skills in bioinformatics and the analysis of genomics data.
We welcome applications from researchers with a strong background in the biological sciences or a quantitative field (mathematics, statistics, computer science, engineering, etc.).
Attendees should have some familiarity with a command-line tool such as UNIX, R or MATLAB, and have some basic statistical knowledge.
All seminars and workshops will be held in English, and a good command of the language is a prerequisite.
You will need a Google account and Google Drive with at least 2GB free storage space. For more details about the platform please have a look here.
Instructors
Eleftheria Zeggini
Director, Institute of Translational Genomics, Helmholtz Centre Munich
Ozvan Bocher
Postdoctoral Fellow, Institute of Translational Genomics, Helmholtz Centre Munich
Konstantinos Hatzikotoulas
Senior Staff Scientist, Institute of Translational Genomics, Helmholtz Centre Munich
Loz Southam
Senior Staff Scientist, Institute of Translational Genomics, Helmholtz Centre Munich
Ana Arruda
PhD Candidate, Institute of Translational Genomics, Helmholtz Centre Munich
Antigone Dimas
Group Leader Institute for Bioinnovation Biological Sciences Research Center “Alexander Fleming” Athens, Greece
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10:00-11:00 |
Welcome Session and Students Introduction |
| 11:00-11:30 |
Lecture 1: Introduction to complex trait genetics and the genomic aetiology of osteoarthritis. (E. Zeggini)
|
|
11:30-12:00
|
Student project Workshop introduction (A. Arruda) |
|
11:30-12:00 |
Lunch break and student project preparation |
| 12:00-13:30 |
Workshop 1: Basic UNIX (optional) Working with the command line, listing and editing files and directories. and/or Advanced UNIX File reformatting, pipelines, subshells and scripts. (K. Hatzikotoulas, L. Southam)
|
| 13:30-14:00 |
Break
|
| 14:00-15:00 |
Lecture 2: Current tools and best practices for performing genome-wide association scans (K. Hatzikotoulas)
|
| 15:00- 17:00 |
Workshop 2: Quality Control for genome-wide association scans Calculating and visualising quality metrics for excluding samples and variants. (K. Hatzikotoulas, L. Southam)
|
| 17:00-17:30 |
Student project workshop
|
| 10:00-11:00 |
Lecture 3 The statistics of genome-wide association studies (O. Bocher) |
| 11:00-12:30 |
Workshop 3 Performing a genome-wide association study: from data preparation to analysis of results. (L. Southam, A. Arruda) |
| 12:30-13:30 |
Lunch break and student project preparation |
| 13:30-14:30 |
Lecture 4 (O. Bocher) |
| 14:30-16:00 |
Workshop 4 Meta-analysis workshop Accessing published results, data preparation, meta-analysis and quality control. (L. Southam, O. Bocher) |
| 16:00-17:00 |
Student project workshop |
| 10:00-11:00 |
Lecture/Workshop 5 Publicly available bioinformatics resources Examining the results of a genome-wide association scan. Functionality of variants, previous associations, genomic context. (K. Hatzikotoulas) |
| 11:00-12:00 |
Lecture 6 (A. Arruda, O. Bocher) |
| 12:00-13:00 |
Lunch break and student project preparation |
| 13:00-15:00 |
Workshop 6 A guide to performing polygenic score analyses. (A. Arruda, O. Bocher) |
| 15:00-17:00 |
Student project workshop |
| 10:00-11:00 |
Lecture 7 Molecular QTL mapping in humans (O. Bocher) |
| 11:00-12:30 |
Workshop 7 Molecular QTL mapping in humans workshop Omics data, including genomics, transcriptomics, proteomics, metabolomics, and epigenomics are increasingly used in GWAS field. (A. Arruda) |
| 12:30-13:30 |
Lunch break, VSS photo and student project preparation |
| 13:30-16:00 |
Presentations and Q&A session (Students) |
| 16:00-16:30 |
Closing remarks by Eleftheria Zeggini |
Registration
REGISTRATION DEADLINE
17 March 2023
CHOSEN PARTICIPANTS WILL BE NOTIFIED BY
1 May 2023
FEES
The course is free for all participants. Students should arrange their own accommodation and transportation. Limited bursaries will be available. Please state in your application if you would like to be considered for a bursary and provide full justification.
LANGUAGE
The courses and workshop will be held in English, and students should also use English when submitting their application.
SELECTION CRITERIA
There are twenty (20) full places for this course. Applicants will be evaluated on the basis of the following criteria:
- Expressed motivation of the participant. Students should submit a personal statement explaining their motivation behind attending the summer school, what they hope to learn and how the skills gained during their attendance will help them in future career plans
- Familiarity with a command-line tool such as UNIX, R or MATLAB
- Basic statistical knowledge
- Recommendations from their group’s principal investigator
Apply now!
To apply, please provide the following documents:
✓ Curriculum vitae (CV)
✓ Letter of recommendation
✓ Personal statement (see above)
Send the above to
candidates@volossummerschool.org
before 17.03.2023
Local Organisers
Zissis Mamuris
Professor of Animal Population Genetics, University of Thessaly
Chronis Velentzas
PhD, Department of Electrical and Computer Engineering, University of Thessaly
